Explore the fascinating world of G-quadruplex DNA structures and their detection in mammalian cells. Learn about their architecture, biological significance, and research methods.
Discover how large genomic alterations in DNA repair genes are linked to early-onset colorectal cancer and the groundbreaking discovery of complex de novo mutations.
Explore how platinum-based anticancer drugs target DNA, the challenges of chromatin packaging, and the future of cancer chemotherapy.
Discover how bioorthogonal chemistry and diazirine-based probes are revolutionizing epigenetic research by revealing DNA's hidden modifications.
Explore how Topoisomerase I inhibitors are revolutionizing cancer treatment by targeting DNA replication in cancer cells.
Discover the molecular basis of the genetic code - the universal language that directs protein synthesis in all living organisms and how scientists are rewriting it.
Discover how template-assembled synthetic G-quadruplexes are revolutionizing our understanding of DNA architecture and enabling breakthroughs in medicine and nanotechnology.